Autogenous Tissue-Engineered Cartilage

Autogenous tissue-engineered cartilage: evaluation as an implant material.

OBJECTIVES To determine whether autogenous tissue-engineered cartilage grafts can be synthesized in predetermined shapes, to compare tissue-engineered cartilage with native cartilage with respect to histological characteristics and biomechanical properties, and to demonstrate how multiple transplantations affect tissue-engineered cartilage. DESIGN Controlled, prospective animal study. SUBJE...

Decellularized Cartilage as a Scaffold for Tissue Engineered Cartilage

The Tissue Engineered Approaches for Cartilage Repair

Technological improvements in biology, medicine, chemistry, engineering and material science have allowed deeper insights into the architectural and molecular organization levels of tissues and materials, providing innovative approaches and tools for medical treatments. One of the therapeutic targets that may benefit from these new issues is damaged human articular cartilage, a tissue unable to...

Modeling the development of tissue engineered cartilage

A finite-element approach was formulated, aimed at enabling an integrated study of mechanical and biochemical factors that control the functional development of tissue engineered constructs. A nonlinear biphasic displacement-velocity-pressure description was combined with advective and diffusive solute transport, uptake and biosynthesis. To illustrate the approach we focused on the synthesis an...

Tissue Engineered Cartilage Patches for Laryngotracheal Reconstruction

Galway, Ireland Tissue Engineered Cartilage Patches for Laryngotracheal Reconstruction James E. Dennis, David Gilpin, Mark Weidenbecher, Corresponding Author: [email protected] Case Western Reserve University, Cleveland, OH, USA and University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH USA Introduction Currently, the treatment for tracheal stenosis in infants is ...